Details

Autor(en) / Beteiligte

• Bhatia, Kunwar S.S
• Cho, Carmen C.M
• Tong, Cina S.L
• Yuen, Edmund H.Y
• Ahuja, Anil T

Titel

Shear Wave Elasticity Imaging of Cervical Lymph Nodes

Ist Teil von

• Ultrasound in medicine & biology, 2012-02, Vol.38 (2), p.195-201

Ort / Verlag

New York, NY: Elsevier Inc

Erscheinungsjahr

2012

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• Abstract A pilot study of real-time shear wave ultrasound elastography (SWE) for cervical lymphadenopathy in routine clinical practice was conducted on 55 nodes undergoing conventional ultrasound (US) with US-guided needle aspiration for cytology. Elastic moduli of stiffest regions in nodes were measured on colour-coded elastograms, which were correlated with cytology. Malignant nodes (n = 31, 56.4%) were stiffer (median 25.0 kPa, range 6.9–278.9 kPa) than benign nodes (median 21.4 kPa, range 8.9–30.2 kPa) (p = 0.008, Mann Whitney U test). A cut-off of 30.2 kPa attained highest accuracy of 61.8%, corresponding to 41.9% sensitivity, 100% specificity and 0.77 area under the receiver operating characteristic curve. Qualitatively, elastograms of benign nodes were homogeneously soft; malignant nodes were homogeneously soft or markedly heterogeneous with some including regions lacking elasticity signal. SWE is feasible for neck nodes. It appears unsuitable for cancer screening but may detect a subset of malignant nodes. The cause of spatial heterogeneity of malignant nodes on SWE is yet to be established.