Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist gegebenenfalls nur via VPN oder Shibboleth (DFN-AAI) möglich. mehr Informationen...
New and existing pharmacotherapeutic options for persistent asthma and COPD
Ist Teil von
Netherlands journal of medicine, 2011-11, Vol.69 (11-12), p.486-499
Ort / Verlag
Alphen aan den Rijn: Van zuiden
Erscheinungsjahr
2011
Quelle
MEDLINE
Beschreibungen/Notizen
Asthma and COPD are chronic inflammatory airway disorders with systemic manifestations. The two diseases have different airway inflammation, features of airway remodelling with subsequent pathophysiology and clinical presentation. The international management guidelines recommend stepwise pharmacotherapy depending on disease control and÷or disease stage, comprising relievers and overall uniform controller treatment, despite the heterogeneity across the conditions and treatment response. Despite effective medications per se, still too many patients remain uncontrolled and no treatment can definitely cure either of the conditions. This overview includes currently recommended pharmacotherapeutic options with novel and future treatment targets.