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Preexposure prophylaxis and timed intercourse for HIV-discordant couples willing to conceive a child
Ist Teil von
AIDS (London), 2011-10, Vol.25 (16), p.2005-2008
Ort / Verlag
Hagerstown, MD: Lippincott Williams & Wilkins
Erscheinungsjahr
2011
Link zum Volltext
Quelle
MEDLINE
Beschreibungen/Notizen
Many HIV-discordant couples express a strong wish to conceive a child. Insemination with processed semen is offered to these couples in many countries. Given the very low level of transmission risk during fully suppressive antiretroviral therapy, we offered timed intercourse combined with preexposure prophylaxis to further reduce the transmission risk. In 53 cases, natural conception was attempted using the proposed method. Pregnancy rates were high and reached a plateau of 75% after six cycles. Advanced age in the female partner was a predictor for infertility in these couples.