Details

Autor(en) / Beteiligte

• Cramer, S. Alan
• Jenkins, David M

Titel

Synthesis of Aziridines from Alkenes and Aryl Azides with a Reusable Macrocyclic Tetracarbene Iron Catalyst

Ist Teil von

• Journal of the American Chemical Society, 2011-12, Vol.133 (48), p.19342-19345

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2011

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A new iron aziridination catalyst supported by a macrocyclic tetracarbene ligand has been synthesized. The catalyst, [(Me,EtTC Ph )Fe(NCCH3)2](PF6)2, was synthesized from the tetraimidazolium precursor (Me,EtTC Ph )(I)4 and characterized by NMR spectroscopy, electrospray ionization mass spectrometry, and single-crystal X-ray diffraction. This iron complex catalyzes the aziridination of electron-donating aryl azides and a wide variety of substituted aliphatic alkenes, including tetrasubstituted ones, in a “C2 + N1” addition reaction. Finally, the catalyst can be recovered and reused up to three additional times without significant reduction in yield.