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In May 2011, an outbreak of the hemolytic–uremic syndrome associated with Shiga-toxin–producing
Escherichia coli
O104:H4 occurred in northern Germany. In this report, the investigation identified sprouts as the likely transmission vehicle.
Human infection with Shiga-toxin–producing
Escherichia coli
is a major cause of postdiarrheal hemolytic–uremic syndrome. This life-threatening disorder, which is characterized by acute renal failure, hemolytic anemia, and thrombocytopenia, typically affects children under the age of 5 years. Shiga-toxin–producing
E. coli
O157 is the serogroup that is most frequently isolated from patients with the hemolytic–uremic syndrome worldwide.
1
In May 2011, a large outbreak of the hemolytic–uremic syndrome associated with the rare
E. coli
serotype O104:H4 occurred in Germany.
2
–
5
The main epidemiologic features were that the peak of the epidemic was reached on May 21 and May 22
4
,
5
and that . . .