Details

Autor(en) / Beteiligte

• Varma, M. C.
• Kushner, Y. B.
• Ko, D. S.
• Kawai, T.
• Martins, P.
• Kaur, P.
• Markmann, J. F.
• Kotton, C. N.

Titel

Early Onset Adenovirus Infection after Simultaneous Kidney–Pancreas Transplant

Ist Teil von

• American journal of transplantation, 2011-03, Vol.11 (3), p.623-627

Ort / Verlag

Malden, USA: Blackwell Publishing Inc

Erscheinungsjahr

2011

Link zum Volltext

Quelle

Wiley Online Library Journals Frontfile Complete

Beschreibungen/Notizen

• Adenoviruses (AdV) are increasingly recognized as important viral pathogens in immunocompromised hosts. The clinical spectrum ranges from asymptomatic viremia to allograft dysfunction, and death. Most of the medical literature is on AdV infection in children and bone marrow transplant recipients. We report a case of AdV in an adult recipient in the first month after simultaneous kidney–pancreas transplant with thymoglobulin induction. This is a rare report of adenovirus infection after multiorgan transplant, and is unique in that it exhibited tissue invasive disease without any localizing signs or allograft dysfunction, while other cases in medical literature had invasive disease of the allograft with allograft dysfunction, failure, or death. In addition, this is the first report of a radiologic presentation of AdV nephritis. This case report provides insights into the clinical presentation and subsequent diagnosis and treatment of adenovirus infection in a simultaneous kidney‐pancreas transplant patient.