Details

Autor(en) / Beteiligte

• Ad De, Ruiter
• Meijer, Gert
• Dormaar, Titiaan
• Janssen, Nard
• Van Der Bilt, Andries
• Slootweg, Piet
• De Bruijn, Joost
• Van Rijn, Linda
• Koole, Ronald

Titel

β-TCP versus Autologous Bone for Repair of Alveolar Clefts in a Goat Model

Ist Teil von

• The Cleft palate-craniofacial journal, 2011-11, Vol.48 (6), p.654-662

Ort / Verlag

Los Angeles, CA: SAGE Publications

Erscheinungsjahr

2011

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Objective The aim of this study in goats was to test the hypothesis that a novel synthetic bone substitute beta tricalcium phosphate (β-TCP) can work as well as autologous bone harvested from the iliac crest for grafting and repair of alveolar clefts. Design Ten adult Dutch milk goats (Capra hircus) were used in a split-mouth study design. Main outcome measures Volumetric histologic assessment of new bone formation and radiographic measurement of orthodontic movement of teeth in a formerly created alveolar cleft. Conclusions The synthetic bone substitute β-TCP was shown to result in bone healing similar to that of iliac crest bone. The surgical, orthodontic, and histologic results now warrant the testing of β-TCP in the human cleft situation.