Details

Autor(en) / Beteiligte

• Ganesh, Venkataraman
• Sudhir, V. Sai
• Kundu, Taraknath
• Chandrasekaran, Srinivasan

Titel

10 Years of Click Chemistry: Synthesis and Applications of Ferrocene-Derived Triazoles

Ist Teil von

• Chemistry, an Asian journal, 2011-10, Vol.6 (10), p.2670-2694

Ort / Verlag

Weinheim: WILEY-VCH Verlag

Erscheinungsjahr

2011

Quelle

MEDLINE

Beschreibungen/Notizen

• Click chemistry has played a significant role as a rapid and versatile strategy for conjugating two molecular fragments under very mild reaction conditions. Introduction of ferrocene‐derived triazole systems using click chemistry has attracted enormous interest in various fields due to its potential applications in electrochemical techniques for detection and sensing. The present discussion focuses on the synthesis of ferrocene–triazole and the importance of using a CuAAC reaction for such conjugation. Applications of ferrocene‐based click reactions in conjugate chemistry, asymmetric catalysis, medicinal chemistry, host–guest interactions, and materials chemistry have been highlighted. Focus on ferrocene: We discuss the synthesis of ferrocene–triazole and the importance of using a copper‐catalyzed azide–alkyne cycloaddition (CuAAC) reaction for the conjugation of two molecular fragments. We also highlight applications of ferrocene‐based click reactions in conjugate chemistry, asymmetric catalysis, medicinal chemistry, host–guest interactions, and materials chemistry (see graphic).