Details

Autor(en) / Beteiligte

• Ahn, Ji Yong, MD
• Jung, Hwoon-Yong, MD, PhD, AGAF
• Choi, Kee Don, MD, PhD
• Choi, Ji Young, MD
• Kim, Mi-Young, MD
• Lee, Jeong Hoon, MD
• Choi, Kwi-Sook, MD
• Kim, Do Hoon, MD
• Song, Ho June, MD, PhD
• Lee, Gin Hyug, MD, PhD
• Kim, Jin-Ho, MD, PhD
• Park, Young Soo, MD, PhD

Titel

Endoscopic and oncologic outcomes after endoscopic resection for early gastric cancer: 1370 cases of absolute and extended indications

Ist Teil von

• Gastrointestinal endoscopy, 2011-09, Vol.74 (3), p.485-493

Ort / Verlag

Maryland heights, MO: Mosby, Inc

Erscheinungsjahr

2011

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• Background Current guidelines for endoscopic management such as EMR and endoscopic submucosal dissection (ESD) in early gastric cancer (EGC) are in evolution, with broader indication criteria. Objective To determine the clinical outcomes of endoscopic treatment, based on absolute indication and extended indication criteria and endoscopic methods. Design Retrospective study. Setting Tertiary-care, academic medical center. Patients EMR or ESD was performed on 1627 cases of EGC in 1447 patients from July 1994 to January 2009. Intervention EMR and ESD. Main Outcome Measurements Clinical outcomes of EGC after EMR or ESD, based on the indication criteria. Results Although the complete resection rate was higher (95.9% vs 88.4%; P < .001), and the complication rate was lower (6.8% vs 9.8%; P = .054) in the absolute than in the extended indication group, there was no between-group difference in the local recurrence rate (0.9% vs 1.1%; P = .783) at a median follow-up period of 32 months (interquartile range 22-48 months). In the extended indication group, ESD resulted in a significantly higher complete resection rate than EMR (83.0% vs 91.1%; P = .006). Limitations Retrospective study. Conclusion ESD in the extended indication group showed acceptable clinical outcomes with a relatively high complete resection rate and a low local recurrence rate.