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Plasma-sprayed hydroxyapatite coating on carbon/carbon composite scaffolds for bone tissue engineering and related tests in vivo
Journal of biomedical materials research. Part A, 2010-03, Vol.92A (3), p.1019-1027
Cao, Ning
Dong, Jianwen
Wang, Qiangxiu
Ma, Quansheng
Wang, Feng
Chen, Huaying
Xue, Chengqian
Li, Musen
2010
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Cao, Ning
Dong, Jianwen
Wang, Qiangxiu
Ma, Quansheng
Wang, Feng
Chen, Huaying
Xue, Chengqian
Li, Musen
Titel
Plasma-sprayed hydroxyapatite coating on carbon/carbon composite scaffolds for bone tissue engineering and related tests in vivo
Ist Teil von
Journal of biomedical materials research. Part A, 2010-03, Vol.92A (3), p.1019-1027
Ort / Verlag
Hoboken: Wiley Subscription Services, Inc., A Wiley Company
Erscheinungsjahr
2010
Quelle
Wiley Online Library All Journals
Beschreibungen/Notizen
The bioactive hydroxyapatite (HA) coatings were successfully prepared on carbon/carbon composites (C/C) by means of sand‐blasting pretreatment and plasma‐spraying technology. X‐ray diffraction was employed to analyze the phase constitute of the coatings. Meanwhile, the bond strength between the HA coatings and C/C substrates was determined via shear test. Experimental results show that the coatings constitute HA, CaO, and other amorphous phosphates. The post heat treatment could effectively increase crystallization and purity of the coatings. Through observation and analysis by electron microprobe and scanning electron microscopy, it is concluded that the bond strength of the plasma‐sprayed HA coatings on C/C is mainly determined by the interface structure and can be further improved by the post heat treatment. Meanwhile, the implantation in vivo was carried out in hybrid goats. The histological observation revealed that the osteoplaque gradually grew on the surface of the HA coatings and the pure C/C surface was covered by the fibrous tissues. No inflammation symptoms were found in the bone tissue around the implants. © 2009 Wiley Periodicals, Inc. J Biomed Mater Res, 2010
Sprache
Englisch
Identifikatoren
ISSN: 1549-3296, 1552-4965
eISSN: 1552-4965
DOI: 10.1002/jbm.a.32424
Titel-ID: cdi_proquest_miscellaneous_883025921
Format
–
Schlagworte
Animals
,
Biocompatibility
,
Biological and medical sciences
,
Biomedical materials
,
Biotechnology
,
Bone and Bones
,
Bones
,
Carbon
,
carbon/carbon composites
,
Coating
,
Durapatite
,
Fundamental and applied biological sciences. Psychology
,
Goats
,
Health. Pharmaceutical industry
,
Heat treatment
,
histology
,
Hydroxyapatite
,
Industrial applications and implications. Economical aspects
,
interface
,
Male
,
Medical sciences
,
Microscopy, Electron, Scanning
,
Miscellaneous
,
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
,
Surgical implants
,
Technology. Biomaterials. Equipments
,
Tissue Engineering
,
X-Ray Diffraction
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