Details

Autor(en) / Beteiligte

• Ferrando, Sara
• Gallus, Lorenzo
• Gambardella, Chiara
• Amaroli, Andrea
• Vallarino, Mauro
• Tagliafierro, Grazia

Titel

Immunolocalization of G protein alpha subunits in the olfactory system of Polypterus senegalus (Cladistia, Actinopterygii)

Ist Teil von

• Neuroscience letters, 2011-07, Vol.499 (2), p.127-131

Ort / Verlag

Shannon: Elsevier Ireland Ltd

Erscheinungsjahr

2011

Quelle

Elsevier ScienceDirect Journals

Beschreibungen/Notizen

• [Display omitted] ► G protein alpha subunits are immunodetected in the olfactory organs of the bichir. ► Gαolf-like immunoreactivity is detected in the ciliated receptor neurons. ► Gαolf-like immunoreactive glomeruli are in the ventral-posterior part of the bulb. ► Gαo-like-like immunoreactivity is detected in microvillous and crypt receptor neurons. ► Gαo-like-like immunoreactive glomeruli are in the anterior part of the olfactory bulb. In vertebrates, the receptor neurons of the olfactory/vomeronasal systems express different receptor gene families and related G-protein types (in particular the G protein alpha subunit). There are no data in the literature about the molecular features of the olfactory/vomeronasal systems of Cladistia thus, in this work, the presence and distribution of different types of G protein alpha subunits were investigated in the olfactory organs of the bichir Polypterus senegalus, using immunohistochemistry. Gαo-like immunoreactivity was detected in the microvillous receptor neurons, with the cell body in the basal zone of the sensory epithelium, and in the crypt neurons. Gαo-like ir glomeruli were mainly localized in the anterior part of the olfactory bulb. Gαolf-like immunoreactivity in the sensory epithelium was detected in the ciliated receptor neurons, while the immunoreactive glomeruli in the olfactory bulb were mainly localized in the ventral–posterior part. No Gαq nor Gαi3 immunoreactivity was detected. These data are partially in agreement with studies that show the distribution of G protein alpha subunits in teleosts, allowing to hypothesize a common organization of the olfactory/vomeronasal systems in the group of Actinopterigians.