Biochemical genetics, 2011-06, Vol.49 (5-6), p.385-394
2011
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- Autor(en) / Beteiligte
- Titel
- Polymorphism in the Prolactin Promoter and Its Association with Growth Traits in Chickens
- Ist Teil von
- Biochemical genetics, 2011-06, Vol.49 (5-6), p.385-394
- Ort / Verlag
- Boston: Springer US
- Erscheinungsjahr
- 2011
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- The pituitary hormone prolactin has a wide variety of functions involving growth, behavioral, and ovarian activities in chickens. The objectives of the present study were to identify polymorphisms in the prolactin promoter and estimate their effects on growth traits in White Leghorn chickens. Among 28 haplotypes found, the h1 haplotype was predominant. Body weight at 16 and 64 weeks and age at sexual maturity were significantly associated with haplotype combinations ( P < 0.05). The h1/h1 haplogroup showed the highest body weight at 16 weeks of age, and h1/h7 was the highest at 64 weeks. The lowest age at sexual maturity was found in birds with the h1/h6 haplotype combination, and mRNA expression of prolactin was lowest in h1/h4 birds and highest in h1/h5 birds. The prolactin promoter was highly polymorphic and had significant associations with growth traits in White Leghorn chickens.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0006-2928eISSN: 1573-4927DOI: 10.1007/s10528-010-9415-3Titel-ID: cdi_proquest_miscellaneous_876226459
- Format
- –
- Schlagworte
- Animals, Base Sequence, Biochemistry, Biomedical and Life Sciences, Biomedicine, Birds, Body weight, Body Weight - genetics, Chickens, Chickens - genetics, Chickens - growth & development, Gene Expression Profiling, Genetic Association Studies, Haplotypes, Human Genetics, Likelihood Functions, Medical Microbiology, Molecular Sequence Data, Polymorphism, Single Nucleotide, Poultry, Prolactin - genetics, Prolactin - metabolism, Promoter Regions, Genetic, Sequence Alignment, Sequence Analysis, DNA, Sexual Maturation - genetics, Sexual maturity, Zoology