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Domestic exposure to aeroallergens in Hong Kong families with asthmatic children
Pediatric pulmonology, 2011-07, Vol.46 (7), p.632-639
Leung, Ting F.
Wong, Yun S.
Chan, Iris H.S.
Yung, Edmund
Sy, Hing Y.
Lam, Christopher W.K.
Wong, Gary W.K.
2011
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Leung, Ting F.
Wong, Yun S.
Chan, Iris H.S.
Yung, Edmund
Sy, Hing Y.
Lam, Christopher W.K.
Wong, Gary W.K.
Titel
Domestic exposure to aeroallergens in Hong Kong families with asthmatic children
Ist Teil von
Pediatric pulmonology, 2011-07, Vol.46 (7), p.632-639
Ort / Verlag
Hoboken: Wiley Subscription Services, Inc., A Wiley Company
Erscheinungsjahr
2011
Quelle
MEDLINE
Beschreibungen/Notizen
Indoor aeroallergen exposures increased asthma symptoms in Caucasians, but their determinants and relationship to asthma and allergy in Asians are unclear. This study investigated exposures to cat, cockroach, and Blomia tropicalis allergens in 115 Hong Kong families with asthmatic children. Patients underwent exhaled nitric oxide and spirometric measurements. Home visits were made within 2 weeks during which parents completed a standardized questionnaire. Fel d 1, Bla g 2, and Blo t 5 in dust samples collected from patients' mattresses, bedroom floors, and living room floors were measured by immunoassays. These aeroallergens were only detectable in some homes (38–55% for Fel d 1; 9–21% for Bla g 2, and 7–14% for Blo t 5). The presence of cat and/or dog was a strong determinant for Fel d 1 in all indoor sites. The timing and frequency of bedding change was associated with Bla g 2 levels, whereas the timing of bedroom floor cleaning was a consistent factor for Blo t 5 levels. Asthmatic children in families with high allergen exposure were more likely to have ≥4 wheezing attacks in preceding 12 months and exercise‐induced wheezing than those with normal allergen exposure (P = 0.051 and 0.030, respectively). Mattress levels of all three allergens were also associated with severity of several allergy symptoms (P = 0.025–0.005). None of these aeroallergens correlated with exhaled nitric oxide and spirometric parameters. This study identifies determinants for cat, cockroach, and B. tropicalis levels in Hong Kong families with asthmatic children. These exposures are associated with severity of allergy symptoms. Pediatr. Pulmonol. 2011; 46:632–639. © 2011 Wiley‐Liss, Inc.
Sprache
Englisch
Identifikatoren
ISSN: 8755-6863
eISSN: 1099-0496
DOI: 10.1002/ppul.21391
Titel-ID: cdi_proquest_miscellaneous_871967015
Format
–
Schlagworte
Adolescent
,
aeroallergen
,
Air Pollution, Indoor - adverse effects
,
Allergens - analysis
,
Animals
,
asthma
,
Asthma - etiology
,
Asthma - immunology
,
Biological and medical sciences
,
Breath Tests
,
Cats
,
Child
,
Chronic obstructive pulmonary disease, asthma
,
Cockroaches
,
Dogs
,
Environmental Exposure - analysis
,
exhaled nitric oxide
,
Female
,
Hong Kong
,
house dust
,
Humans
,
Luminescent Measurements
,
lung function
,
Male
,
Medical sciences
,
Mites
,
Nitric Oxide - analysis
,
Pneumology
,
Spirometry
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