Details

Autor(en) / Beteiligte

• HATOYA, Singo
• KUMAGAI, Daijiro
• TAKEDA, Seiko
• YAMAMOTO, Emi
• NAKANISHI, Masako
• KUWAMURA, Mitsuru
• SUGIURA, Kikuya
• SASAI, Hiroshi
• YAMATE, Jyoji
• INABA, Toshio

Titel

Successful Management with CHOP for Pulmonary Lymphomatoid Granulomatosis in a Dog

Ist Teil von

• Journal of Veterinary Medical Science, 2011, Vol.73(4), pp.527-530

Ort / Verlag

Japan: JAPANESE SOCIETY OF VETERINARY SCIENCE

Erscheinungsjahr

2011

Quelle

MEDLINE

Beschreibungen/Notizen

• A 3-year-old, spayed female miniature dachshund was presented for vomiting and anorexia. Thoracic radiographs and CT scan revealed abnormal pulmonary opacities at bilateral caudal lobe. Cytological analysis of the pulmonary mass revealed the presence of large lymphohistiocytic cells and small lymphocytes with occasional neutrophils and plasma cells. An open lung biopsy was performed and a diagnosis of pulmonary lymphomatoid granulomatosis (LYG) was made. The dog was administered CHOP based therapy (modified UW-25), and it survived for 1,022 days after admission. Immunohistochemistry revealed pulmonary lesions consisted of many CD79a positive B cells aggregation and proliferation with prominent angiocentric pattern. This was the first case of canine pulmonary LYG managed by CHOP chemotherapy.