Details

Autor(en) / Beteiligte

• Choi, Kwi-Sook, MD, PhD
• Jung, Hwoon-Yong, MD, PhD, AGAF
• Choi, Kee Don, MD, PhD
• Lee, Gin Hyug, MD, PhD
• Song, Ho June, MD, PhD
• Kim, Do Hoon, MD
• Lee, Jeong Hoon, MD
• Kim, Mi-Young, MD
• Kim, Byung Sik, MD, PhD
• Oh, Sung Tae, MD, PhD
• Yook, Jeong Hwan, MD, PhD
• Jang, Se Jin, MD, PhD
• Yun, Sung-Cheol, PhD
• Kim, Seon Ok
• Kim, Jin-Ho, MD, PhD

Titel

EMR versus gastrectomy for intramucosal gastric cancer: comparison of long-term outcomes

Ist Teil von

• Gastrointestinal endoscopy, 2011-05, Vol.73 (5), p.942-948

Ort / Verlag

Maryland heights, MO: Mosby, Inc

Erscheinungsjahr

2011

Quelle

MEDLINE

Beschreibungen/Notizen

• Background Limited data exist regarding the long-term outcomes of EMR compared with gastrectomy. Objective To compare the long-term outcomes after EMR and surgery. Design Retrospective analysis with propensity-score matching. Setting Tertiary care center. Patients This study involved 215 patients with intramucosal gastric cancer completely removed by EMR and 843 patients who underwent curative surgical resection between January 1997 and August 2002. Propensity-score matching yielded 551 matched patients. Interventions EMR versus surgery. Main Outcome Measurements Death and recurrence. Results In the matched cohort, there were no significant between-group differences in the risk of death (hazard ratio [HR] for the EMR group 1.39; 95% CI, 0.87-2.23) or recurrence (HR 1.18; 95% CI, 0.22-6.35). Although patients who underwent EMR had higher risk of metachronous gastric cancers (HR 6.72; 95% CI, 2.00-22.58), all recurrent or metachronous gastric cancers after EMR were successfully re-treated without affecting overall survival. Although complication rates were similar (odds ratio 0.84; 95% CI, 0.41-1.70), there were no mortalities in the EMR group compared with 2 in the surgery group. The EMR group had a significantly shorter hospital stay (median 8 days, interquartile range [IQR] 6-11 days vs 15 days, IQR 12-19 days; P < .001) and lower cost of care ($2049, IQR $1586-2425 vs $4042, IQR $3458-4959; P < .001). Limitations Retrospective, nonrandomized study. Conclusions EMR was comparable to surgery in terms of risk of death and recurrence. Because of its lower medical costs and shorter duration of hospital stay, EMR has advantages over surgery.