Details

Autor(en) / Beteiligte

• Ness, Peter J., MD
• Werner, Liliana, MD, PhD
• Maddula, Surekha, MD
• Davis, Don, MD
• Zaugg, Brian, BS
• Stringham, Jack, BS
• Burrow, Michael
• Yeh, Oliver, BS

Titel

Pathology of 219 human cadaver eyes with 1-piece or 3-piece hydrophobic acrylic intraocular lenses: Capsular bag opacification and sites of square-edged barrier breach

Ist Teil von

• Journal of cataract and refractive surgery, 2011-05, Vol.37 (5), p.923-930

Ort / Verlag

New York, NY: Elsevier Inc

Erscheinungsjahr

2011

Quelle

MEDLINE

Beschreibungen/Notizen

• Purpose To assess capsular bag opacification and sites of initial posterior capsule opacification (PCO) in human cadaver eyes with square-edged 1-piece or 3-piece hydrophobic acrylic intraocular lenses (IOLs). Setting John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. Design Experimental study. Methods Eyes were immersed in 10% formalin after enucleation and had anterior segment scanning with very-high-frequency ultrasound (Artemis). After the eyes were sectioned at the equator, gross examination of the anterior segment was performed from the posterior aspect to assess capsular bag opacification, anterior capsule coverage of the IOL edge, and IOL fixation. Selected eyes had histopathologic examination. Results One hundred nineteen eyes with 1-piece IOLs and 100 with 3-piece IOLs were included in the analyses of capsular bag opacification. There was no difference in central ( P =.29) or peripheral ( P =.76) PCO. In 63 of 84 eyes with a 1-piece IOL and peripheral PCO, the optic–haptic junction was the site of initiation. In eyes with a 3-piece IOL, initial peripheral PCO was observed at nearly the same rate whether there was full 360-degree anterior capsulorhexis overlap of the optic or no overlap ( P =.13). In the latter, the site of PCO initiation was in areas lacking capsulorhexis coverage in 46% of eyes. Conclusions There was no difference in central or peripheral PCO between 1-piece and 3-piece hydrophobic acrylic IOLs. With 1-piece IOLs, PCO tended to start at the optic–haptic junctions. With 3-piece IOLs, full anterior capsule coverage did not produce a statistically significant benefit with respect to PCO prevention. Financial Disclosure No author has a financial or proprietary interest in any material or method mentioned.