Details

Autor(en) / Beteiligte

• Deuss, Peter J.
• den Heeten, René
• Laan, Wouter
• Kamer, Paul C. J.

Titel

Bioinspired Catalyst Design and Artificial Metalloenzymes

Ist Teil von

• Chemistry : a European journal, 2011-04, Vol.17 (17), p.4680-4698

Ort / Verlag

Weinheim: WILEY-VCH Verlag

Erscheinungsjahr

2011

Quelle

Wiley Online Library Journals Frontfile Complete

Beschreibungen/Notizen

• Many bioinspired transition‐metal catalysts have been developed over the recent years. In this review the progress in the design and application of ligand systems based on peptides and DNA and the development of artificial metalloenzymes are reviewed with a particular emphasis on the combination of phosphane ligands with powerful molecular recognition and shape selectivity of biomolecules. The various approaches for the assembly of these catalytic systems will be highlighted, and the possibilities that the use of the building blocks of Nature provide for catalyst optimisation strategies are discussed. Inspired by Nature: Enzymes are exceptional catalysts in many ways, but their limited reaction repertoire restricts their application in synthesis routes performed in industry and research laboratories. Nature has inspired researchers to create new classes of transition‐metal catalyst for important chemical conversions. This review highlights the development of catalysts based on natural building blocks and how these systems offer the prospect of new “enzyme‐like” catalysts.