Angewandte Chemie (International ed.), 2011-04, Vol.50 (16), p.3730-3733
International ed. in English, 2011
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Details
- Autor(en) / Beteiligte
- Titel
- Synthesis of (−)-Viriditoxin: A 6,6′-Binaphthopyran-2-one that Targets the Bacterial Cell Division Protein FtsZ
- Ist Teil von
- Angewandte Chemie (International ed.), 2011-04, Vol.50 (16), p.3730-3733
- Auflage
- International ed. in English
- Ort / Verlag
- Weinheim: WILEY-VCH Verlag
- Erscheinungsjahr
- 2011
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Remote control: Vanadium catalysts provide the key to synthesizing the bacteria‐fighting natural product viriditoxin. An achiral catalyst shows modest levels of remote diastereocontrol induced by the lactone stereogenic center and chiral catalysts can be used to enhance or reverse this inherent selectivity.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1433-7851eISSN: 1521-3773DOI: 10.1002/anie.201007298Titel-ID: cdi_proquest_miscellaneous_861204991
- Format
- –
- Schlagworte
- Aspergillus - chemistry, Bacteria - metabolism, Bacterial Proteins - antagonists & inhibitors, Bacterial Proteins - metabolism, biaryls, Catalysis, Crystallography, X-Ray, Cytoskeletal Proteins - antagonists & inhibitors, Cytoskeletal Proteins - metabolism, enantioselective catalysis, Molecular Conformation, Naphthols - chemical synthesis, Naphthols - chemistry, natural product synthesis, Stereoisomerism, Vanadium - chemistry, vanadium catalysis, viriditoxin