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Randomized clinical trial comparing polypropylene or polydioxanone for midline abdominal wall closure
British journal of surgery, 2011-05, Vol.98 (5), p.633-639
Bloemen, A.
van Dooren, P.
Huizinga, B. F.
Hoofwijk, A. G. M.
2011
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Bloemen, A.
van Dooren, P.
Huizinga, B. F.
Hoofwijk, A. G. M.
Titel
Randomized clinical trial comparing polypropylene or polydioxanone for midline abdominal wall closure
Ist Teil von
British journal of surgery, 2011-05, Vol.98 (5), p.633-639
Ort / Verlag
Chichester, UK: John Wiley & Sons, Ltd
Erscheinungsjahr
2011
Quelle
MEDLINE
Beschreibungen/Notizen
Background: Incisional hernia is a frequent complication of abdominal surgery, often requiring surgical intervention. This prospective randomized trial compared suture materials for closure of the fascia after abdominal surgery. Methods: In 456 patients the abdominal fascia was closed with either non‐absorbable (polypropylene; Prolene®) or absorbable (polydioxanone; PDS®) suture material. Follow‐up was by clinical examination and ultrasonography at 6‐month intervals. Outcome measures were incisional hernia, surgical‐site infection and suture sinus. Results: Some 223 patients were analysed after closure with Prolene® and 233 after PDS®. Median follow‐up was 32 and 31 months respectively. There was no significant difference in the incidence of incisional hernia between the groups: 20·2 per cent (45 of 223) for Prolene® and 24·9 per cent (58 of 233) with PDS® (P = 0·229). Kaplan‐Meier analysis showed a cumulative rate after 4 years of 23·7 and 30·2 per cent for Prolene® and PDS® respectively (P = 0·222). Secondary outcome measures showed no significant differences. Conclusion: The incidence of incisional hernia in both groups was higher than expected from previous literature. There were no significant differences between the two suture methods. Registration number: ISRCTN65599814 (http://www.clinical‐trials.com). Copyright © 2011 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. Hernias common, but equal
Sprache
Englisch
Identifikatoren
ISSN: 0007-1323
eISSN: 1365-2168
DOI: 10.1002/bjs.7398
Titel-ID: cdi_proquest_miscellaneous_860178834
Format
–
Schlagworte
Abdominal Wall - surgery
,
Biological and medical sciences
,
Female
,
General aspects
,
Hernia, Ventral - prevention & control
,
Humans
,
Kaplan-Meier Estimate
,
Male
,
Medical sciences
,
Middle Aged
,
Polydioxanone - therapeutic use
,
Polypropylenes - therapeutic use
,
Postoperative Complications - prevention & control
,
Prospective Studies
,
Surgical Wound Dehiscence - etiology
,
Surgical Wound Infection - etiology
,
Sutures
,
Treatment Outcome
,
Wound Healing
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