Chemical communications (Cambridge, England), 2011-01, Vol.47 (15), p.4373-4375
2011
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Details
- Autor(en) / Beteiligte
- Titel
- A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production
- Ist Teil von
- Chemical communications (Cambridge, England), 2011-01, Vol.47 (15), p.4373-4375
- Ort / Verlag
- England
- Erscheinungsjahr
- 2011
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- A specific and sensitive fluorescence-based method was developed for the imaging of microbe-induced HOCl production. Furthermore, we demonstrate dual oxidase (DUOX)-mediated HOCl generation in the mucosa of live animals providing a novel insight into mucosal innate immunity.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1359-7345eISSN: 1364-548XDOI: 10.1039/c1cc10589bTitel-ID: cdi_proquest_miscellaneous_859317198
- Format
- –
- Schlagworte
- Animals, Bacterial Physiological Phenomena, Cell Survival, Drosophila melanogaster - immunology, Drosophila melanogaster - microbiology, Fungi - physiology, Humans, Hypochlorous Acid - metabolism, Immunity, Innate, Intestinal Mucosa - metabolism, Intestinal Mucosa - microbiology, Molecular Imaging - methods, NADPH Oxidases - metabolism, Neutrophils - cytology, Neutrophils - microbiology, Phagosomes - metabolism, Rhodamines - chemistry