Details

Autor(en) / Beteiligte

• Malvezzi, Matteo, PhD
• Bonifazi, Martina, MD
• Bertuccio, Paola, ScD
• Levi, Fabio, MD
• La Vecchia, Carlo, MD
• Decarli, Adriano, ScD
• Negri, Eva, ScD

Titel

An Age-Period-Cohort Analysis of Gastric Cancer Mortality from 1950 to 2007 in Europe

Ist Teil von

• Annals of epidemiology, 2010-12, Vol.20 (12), p.898-905

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2010

Quelle

MEDLINE

Beschreibungen/Notizen

• Purpose To analyze the components of the favorable trends in gastric cancer in Europe. Methods From official certified deaths from gastric cancer and population estimates for 42 countries of the European geographical region, during the period 1950 to 2007, age-standardized death rates (World Standard Population) were computed, and an age-period-cohort analysis was performed. Results Central and Northern countries with lower rates in the 2005 to 2007 period, such as France (5.28 and 1.93/100,000, men and women respectively) and Sweden (4.49 and 2.21/100,000), had descending period and cohort effects that decreased steeply from the earliest cohorts until those born in the 1940s, to then stabilize. Former nonmarket economy countries had mortality rates greater than 20/100,000 men and 10/100,000 women, and displayed a later start in the cohort effect fall, which continued in the younger cohorts. Mortality remained high in some countries of Southern and Eastern Europe. Conclusions The decrease in gastric cancer mortality was observed in both cohort and period effects but was larger in the cohorts, suggesting that the downward trends are likely to persist in countries with higher rates. In a few Western countries with very low rates an asymptote appears to have been reached for cohorts born after the 1940s, particularly in women.