Details

Autor(en) / Beteiligte

• Nielsen, Sten Lyager, MD, PhD, DMSc
• Lomholt, Mads, MD, PhD
• Johansen, Peter, PhD
• Hansen, Soeren B., MD, PhD
• Andersen, Niels Trolle, PhD
• Hasenkam, John Michael, MD, DMSc

Titel

Mitral ring annuloplasty relieves tension of the secondary but not primary chordae tendineae in the anterior mitral leaflet

Ist Teil von

• The Journal of thoracic and cardiovascular surgery, 2011-03, Vol.141 (3), p.732-737

Ort / Verlag

New York, NY: Mosby, Inc

Erscheinungsjahr

2011

Link zum Volltext

Quelle

Electronic Journals Library - Freely accessible e-journals

Beschreibungen/Notizen

• Objective Mitral ring annuloplasty is routinely applied as an adjunct procedure in reconstructive surgery on the mitral valve leaflets or chordae tendineae. It is assumed that mitral ring annuloplasty relieves tensile stress on the repaired valve tissue and thereby improves the durability of the procedure, but the indication is disputable. We sought to study the effect of mitral ring annuloplasty on the tension of the primary and secondary chordae tendineae of the anterior mitral valve leaflet in vivo. Methods In 17 adult pigs miniature chordal force transducers were sutured to the 2 major fixing primary chordae and the 2 strut secondary chordae of the anterior leaflet. Baseline measurements were accomplished. After randomization, one group (n = 10) underwent a mitral ring annuloplasty (Carpentier–Edwards Classic, 28 mm; Edwards Lifesciences, Irvine, Calif), and the second group (n = 7) served as controls and underwent a sham operation. Simultaneous recordings of chordae tendineae tension and hemodynamics and echocardiographic assessment of anterior leaflet occlusion area were acquired at baseline and after the mitral ring annuloplasty/sham operation. Results Mitral ring annuloplasty caused a significant reduction of the anterior leaflet occlusion area (1.85 ± 0.16 vs 4.63 ± 0.37 cm2 ) and the tension of the secondary chordae (0.33 ± 0.06 vs 0.67 ± 0.12 N) but did not affect the tension of the primary chordae (0.24 ± 0.07 vs 0.17 ± 0.06 N). The sham procedure had no effect on these variables. Conclusions In normal porcine hearts mitral ring annuloplasty primarily relieves stress on the anterior leaflet belly rather than the leading edge. Mitral ring annuloplasty might therefore protect repairs of the central portion of the anterior leaflet and secondary chordae but not repairs that solely involve the anterior leaflet's leading edge and adjacent chordae.