Details

Autor(en) / Beteiligte

• Pine, Irving
• Engel, Frank L.
• Schwartz, Theodore B.

Titel

The electroencephalogram in acth and cortisone treated patients

Ist Teil von

• Electroencephalography and clinical neurophysiology, 1951-01, Vol.3 (3), p.301-310

Ort / Verlag

Ireland: Elsevier Ireland Ltd

Erscheinungsjahr

1951

Link zum Volltext

Quelle

Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)

Beschreibungen/Notizen

• 1. 1. In 40 courses of therapy (of 37 patients treated with ACTH or cortisone) EEGs were evaluated before and during treatment. 2. 2. The EEG was unchanged in 19 or 47.5 per cent and showed questionable improvement in nine or 22.5 per cent, for a total of 70 per cent. 3. 3. The EEG showed marked or definite improvement during treatment, in 7 of 12 patients in this series who had abnormal control electroencephalograms. Thus, 32.4 per cent of the patients had abnormal pre-treatment records and 58.7 per cent of these showed definite improvement. 4. 4. EEG abnormalities progressed or developed in only four of 37 patients, and in one, the abnormal changes were attributed to the progression of the disease process, and not the effect of the hormone. 5. 5. There was no specific EEG correlation with electrolyte changes and mental changes during the treatment. 6. 6. The occurrence of abnormal EEGs in some patients with rheumatoid arthritis, lupus erythematousus and periarteritis nodosa is noted.