Science (American Association for the Advancement of Science), 1976-07, Vol.193 (4251), p.403-405
1976
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Details
- Autor(en) / Beteiligte
- Titel
- Thyrotropin Releasing Hormone: Development of Inactivation System During Maturation of the Rat
- Ist Teil von
- Science (American Association for the Advancement of Science), 1976-07, Vol.193 (4251), p.403-405
- Ort / Verlag
- United States: American Association for the Advancement of Science
- Erscheinungsjahr
- 1976
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Whereas thyrotropin releasing hormone is rapidly and extensively degraded by plasma of adult rats, no appreciable loss of biological or immunological activity is caused by plasma from rats 4 or 16 days old. The plasma of neonatal rats does not appear to contain an inhibitor of thyrotropin releasing hormone peptidase or a peptidase with altered substrate affinity. The development of an active peptidase in rat plasma suggests a physiological role for inactivation of thyrotropin releasing hormone.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0036-8075eISSN: 1095-9203DOI: 10.1126/science.819993Titel-ID: cdi_proquest_miscellaneous_83374945
- Format
- –
- Schlagworte
- Age Factors, Animals, Animals, Newborn - blood, Blood plasma, Cell lines, Developmental biology, HeLa cells, Hormones, Immunology, Peptide Hydrolases - blood, Plant cells, Rats, Stem cells, Thyrotropin-Releasing Hormone - blood, Thyrotropin-Releasing Hormone - metabolism, Totipotent stem cells