Details

Autor(en) / Beteiligte

• Hinshaw, Lerner B.
• Vick, James A.
• Carlson, Curtis H.
• Fan, You-Ling

Titel

Role of Histamine in Endotoxin Shock.

Ist Teil von

• Experimental biology and medicine (Maywood, N.J.), 1960-07, Vol.104 (3), p.379-381

Ort / Verlag

London, England: SAGE Publications

Erscheinungsjahr

1960

Quelle

MEDLINE

Beschreibungen/Notizen

• Summary Intravenous injection of lethal doses of endotoxin in anesthetized dogs results in rapid decrease in total blood histamine, a concomitant rise in plasma histamine, and increased peripheral vascular responsiveness to histamine. These findings support the view that histamine performs a crucial role in progressive development of hypotension following administration of endotoxin. Figure Appreciation is expressed to Lorentz E. Wittmers for technical assistance.