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Details

Autor(en) / Beteiligte
Titel
2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation (Updating the 2006 Guideline): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
Ist Teil von
  • Journal of the American College of Cardiology, 2011-01, Vol.57 (2), p.223-242
Ort / Verlag
United States: Elsevier Limited
Erscheinungsjahr
2011
Quelle
Access via ScienceDirect (Elsevier)
Beschreibungen/Notizen
  • Specific criteria/considerations for inclusion of new data include the following: publication in a peer-reviewed journal; large, randomized, placebo-controlled trial(s); nonrandomized data deemed important on the basis of results affecting current safety and efficacy assumptions; strength/weakness of research methodology and findings; likelihood of additional studies influencing current findings; impact on current and/or likelihood of need to develop new performance measure(s); request(s) and requirement(s) for review and update from the practice community, key stakeholders, and other sources free of relationships with industry or other potential bias; number of previous trials showing consistent results; and need for consistency with a new guideline or guideline revisions. Ideal candidates for catheter ablation are younger patients with minimal structural abnormalities and multiple symptomatic episodes of paroxysmal AF over time despite appropriate pharmacological therapy. 70% of patients treated by catheter ablation remained free of symptomatic recurrent atrial arrhythmia versus 19% of patients treated with ADT. 95% CI: 0.15 to 0.39; p>0.001 HR: 0.24 63% of patients treated by catheter ablation were free of recurrent atrial arrhythmia versus 17% of patients treated with ADT. 95% CI: 0.18 to 0.45; p<0.001 HR: 0.29 Appendix 3 Summary Table ADT indicates antiarrhythmic drug therapy; AF, atrial fibrillation; ASA, aspirin; AV, atrioventricular; AVB, atrioventricular block; bid, twice a day; bpm, beats per minute; CABG, coronary artery bypass graft surgery; CAD, coronary artery disease; CHF, congestive heart failure; CI: confidence interval; CNS, central nervous system; CYP, cytochrome P; CV, cardiovascular; d, day; DCM, dilated cardiomyopathy; DM, diabetes mellitus; ECG, electrocardiogram; EF, ejection fraction; h, hour; HF, heart failure; HR, hazard ratio; HTN, hypertension; ICD, implantable cardioverter-defibrillator; IV, intravenous; LA, left atrial; LBBB, left bundle-branch block; LV, left ventricular; LVEF, left ventricular ejection fraction; MI, myocardial infarction; mm, millimeter; mo, month; ms, milliseconds; MSE, main safety endpoint; NYHA, New York Heart Association; PAD, peripheral arterial disease; PR interval, interval between onset of P wave and onset of QRS complex on an ECG; PVD, peripheral vascular disease; qd, once per day; RR, relative risk; s, seconds; SD, standard deviation; SOB, short of breath; SR, sinus rhythm; TIA, transient ischemic attack; wk, week; and y, year.

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