Details

Autor(en) / Beteiligte

• PERRIN, J. H.

Titel

A circular dichroic investigation of the binding of fenoprofen, 2(3-phenoxyphenyl)-propionic acid, to human serum albumin

Ist Teil von

• Journal of pharmacy and pharmacology, 1973-03, Vol.25 (3), p.208-212

Ort / Verlag

Oxford, UK: Blackwell Publishing Ltd

Erscheinungsjahr

1973

Quelle

MEDLINE

Beschreibungen/Notizen

• The extrinsic Cotton effects found on the binding of fenoprofen and some of its analogues to human serum albumin have been investigated. The fenoprofen appears to bind hydrophobically to the albumin via the phenyl rings and after dipole interactions of the carbonyl group and the ether oxygen. This binding is non‐stereospecific.