Science (American Association for the Advancement of Science), 1972-11, Vol.178 (4063), p.875-876
1972
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Details
- Autor(en) / Beteiligte
- Titel
- Primary Structure of Neocarzinostatin, an Antitumor Protein
- Ist Teil von
- Science (American Association for the Advancement of Science), 1972-11, Vol.178 (4063), p.875-876
- Ort / Verlag
- United States: American Association for the Advancement of Science
- Erscheinungsjahr
- 1972
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- The antitumor protein neocarzinostatin is an acidic single-chain molecule, cross-linked by two disulfide bridges, and consists of 109 amino acid residues. Complete disulfide bond reduction and S-carboxymethylation was achieved in liquid ammonia. Sequence determination of five tryptic fragments led to the proposed primary structure.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0036-8075eISSN: 1095-9203DOI: 10.1126/science.178.4063.875Titel-ID: cdi_proquest_miscellaneous_81626087
- Format
- –
- Schlagworte
- Amino Acid Sequence, Amino acids, Ammonia, Antibiotics, Antibiotics, Antineoplastic, Chromatography, Gel, Chromatography, Paper, Chymotrypsin, Disulfides, Electrophoresis, Paper, Liquids, Molecules, Paper chromatography, Pepsin A, Peptides - analysis, Proteins, Sequence analysis, Sodium, Thermolysin