Details

Autor(en) / Beteiligte

• Davidheiser, Roger H.
• Figge, Frank H. J.

Titel

Enzymatic Porphyrin Synthesis in Harderian Glands and Other Organs and Tissues of Mice.

Ist Teil von

• Experimental biology and medicine (Maywood, N.J.), 1955-11, Vol.90 (2), p.461-462

Ort / Verlag

London, England: SAGE Publications

Erscheinungsjahr

1955

Quelle

MEDLINE

Beschreibungen/Notizen

• Summary and Conclusions 1. Buffered saline extracts of equal weights of mouse Harderian gland, liver, muscle-bone, and brain homogenates were prepared. 2. Various amounts of these extracts were tested for their capacity to produce porphyrin by adding 1.4 cc of a 0.01 M solution of δ aminolevulinic acid and incubating the mixture in a stoppered Klett tube at 37°C for 24 hours. 3. The Harderian gland displayed the greatest porphyrin-producing enzyme activity, whereas the liver was less than that of Harderian gland but 5 and 7 times as great as muscle-bone and brain respectively. 4. These results led to the conclusion that the Harderian gland is a porphyrin-secreting structure and probably not an excretory type of gland.