Science (American Association for the Advancement of Science), 1984-08, Vol.225 (4664), p.847-849
1984
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Details
- Autor(en) / Beteiligte
- Titel
- Enhancement of Sexual Motivation in Male Rats by Yohimbine
- Ist Teil von
- Science (American Association for the Advancement of Science), 1984-08, Vol.225 (4664), p.847-849
- Ort / Verlag
- Washington, DC: The American Association for the Advancement of Science
- Erscheinungsjahr
- 1984
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Yohimbine hydrochloride, an $\alpha _{2}$-adrenoceptor antagonist, increased sexual motivation in male rats as evidenced by increased mounting performance in mating tests conducted after genital anesthetization, increased percentage of male rats ejaculating in their first heterosexual encounter, and induction of copulatory behavior in sexually inactive male rats. These observations lead to the suggestion that α -adrenoceptors are important modulators of sexual arousal in intact male rats. These results indicate that pharmacological treatment of sexual (libido) dysfunction may be useful.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0036-8075eISSN: 1095-9203DOI: 10.1126/science.6474156Titel-ID: cdi_proquest_miscellaneous_81233619
- Format
- –
- Schlagworte
- Animal sexual behavior, Animals, Aphrodisiacs - pharmacology, Biological and medical sciences, Body weight, Copulation - drug effects, Ejaculation, Ejaculation - drug effects, Genital system. Reproduction, Genitalia, Human sexual behavior, Male, Male animals, Mating behavior, Medical sciences, Motivation - drug effects, Pharmacology, Pharmacology. Drug treatments, Rats, Receptors, Adrenergic - drug effects, Sex drive, Sexual behavior in animals, Sexual Behavior, Animal - drug effects, Vehicle weight, Yohimbine, Yohimbine - pharmacology