Details

Autor(en) / Beteiligte

• Chafe, Weldon
• Fowler, Wesley C.
• Currie, John L.
• Davis, Maxie L.
• Walton, Leslie A.
• Montana, Gustavo

Titel

Single-fraction palliative pelvic radiation therapy in gynecologic oncology: 1,000 rads

Ist Teil von

• American journal of obstetrics and gynecology, 1984-03, Vol.148 (5), p.701-705

Ort / Verlag

Philadelphia, PA: Elsevier Inc

Erscheinungsjahr

1984

Quelle

MEDLINE

Beschreibungen/Notizen

• The management of the patient with advanced gynecologic malignancies presents multiple problems for the gynecologic and radiation oncologists involved in their care. When palliative management only is indicated, conventional treatment protocols occupy a significant portion of the patient's remaining life span, oftentimes with associated morbidity. Single-fraction external radiation therapy, consisting of 1,000 rads to the whole pelvis, was used in 30 patients with advanced gynecologic malignancies to palliate locally advanced pelvic disease. Alleviation of symptoms and maintenance of a reasonable quality of life were obtained in all patients. No untoward acute side effects were observed. Thirteen patients are alive from 2 to 19 months after treatment, with a mean overall survival after treatment of 8.4 months. It is concluded that this regimen should be considered as the palliative therapy of choice for certain patients with advanced gynecologic malignancies.