Details

Autor(en) / Beteiligte

• Macura, Slobodan
• Kumar, Narinder G.
• Brown, Larry R.

Titel

Combined use of COSY and double quantum two-dimensional NMR spectroscopy for elucidation of spin systems in polymyxin B

Ist Teil von

• Biochemical and biophysical research communications, 1983-12, Vol.117 (2), p.486-492

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

1983

Quelle

Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)

Beschreibungen/Notizen

• Two-dimensional single quantum correlation NMR spectroscopy (COSY) and two-dimensional double quantum NMR spectroscopy (2QT) are used to study spin systems in the 1H NMR spectrum of polymyxin B. Because of different frequency relationships, the two types of two-dimensional NMR experiments are found to be highly complementary. This is demonstrated by combined use of COSY and 2QT spectroscopy to obtain a complete analysis of the complicated spectral overlap which occurs in the 1H NMR spectrum of polymyxin B.