Experimental brain research, 1991-01, Vol.84 (3), p.538-544
1991
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Calcium binding proteins and neuropeptides as molecular markers of GABAergic interneurons in the cat visual cortex
- Ist Teil von
- Experimental brain research, 1991-01, Vol.84 (3), p.538-544
- Ort / Verlag
- Berlin: Springer
- Erscheinungsjahr
- 1991
- Quelle
- SpringerLINK Contemporary (Konsortium Baden-Württemberg)
- Beschreibungen/Notizen
- In the cat visual cortex, almost all parvalbumin-positive cells are GABAergic, and about 80% of the calbindin D-28K-positive neurons are also GABA-immunoreactive. About 37% of the GABAergic neurons contain parvalbumin and a smaller fraction (about 18%) contains calbindin. Furthermore, parvalbumin and calbindin are localized in two separate neuronal populations in the cat visual cortex, suggesting that two GABAergic populations can be distinguished, one containing parvalbumin and one containing calbindin. Double staining for parvalbumin and neuropeptides (CCK, SRIF and NPY), revealed no double-labeled cells, with the exception of a few SRIF- and parvalbumin-positive neurons. These results show that cortical GABAergic cells can be differentiated on basis of their calcium binding protein and neuropeptide immunoreactivity.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0014-4819eISSN: 1432-1106DOI: 10.1007/BF00230966Titel-ID: cdi_proquest_miscellaneous_80721287
- Format
- –
- Schlagworte
- Animals, Antibody Specificity, Biological and medical sciences, Biomarkers, Calbindins, Calcium-Binding Proteins - metabolism, Cats, Eye and associated structures. Visual pathways and centers. Vision, Fundamental and applied biological sciences. Psychology, gamma-Aminobutyric Acid - physiology, Immunohistochemistry, Interneurons - metabolism, Neuropeptides - metabolism, Parvalbumins - metabolism, S100 Calcium Binding Protein G - metabolism, Vertebrates: nervous system and sense organs, Visual Cortex - cytology, Visual Cortex - metabolism