Details

Autor(en) / Beteiligte

• Bendich, Adrianne
• Gabriel, Edda
• Machlin, Lawrence J.

Titel

Effect of Dietary Level of Vitamin E on the Immune System of the Spontaneously Hypertensive (SHR) and Normotensive Wistar Kyoto (WKY) Rat

Ist Teil von

• The Journal of nutrition, 1983-10, Vol.113 (10), p.1920-1926

Ort / Verlag

Bethesda, MD: Elsevier Inc

Erscheinungsjahr

1983

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Spontaneously hypertensive rats (SHR) had depressed splenic mitogen responses as well as lower splenic vitamin E when compared to normotensive Wistar Kyoto strain (WKY) rats fed a stock diet. Both strains had depressed T- and B-cell splenic mitogen responses after 17 weeks on a semipurified, vitamin E-deficient diet when compared to animals fed either stock or dl-α-tocopheryl acetate-supplemented semipurified diet. In addition, SHR fed the vitamin E-supplemented diet had enhanced thymocyte rosetting compared to those fed the vitamin E-deficient diet. In contrast, the dietary vitamin E level did not affect the thymocyte rosetting in WKY rats.