Details

Autor(en) / Beteiligte

• Platt, Orah S
• Thorington, Bruce D
• Brambilla, Donald J
• Milner, Paul F
• Rosse, Wendell F
• Vichinsky, Elliott
• Kinney, Thomas R

Titel

Pain in Sickle Cell Disease: Rates and Risk Factors

Ist Teil von

• The New England journal of medicine, 1991-07, Vol.325 (1), p.11-16

Ort / Verlag

Boston, MA: Massachusetts Medical Society

Erscheinungsjahr

1991

Quelle

MEDLINE

Beschreibungen/Notizen

• PERIODIC, self-limited episodes of excruciating musculoskeletal pain punctuate the lives of patients with sickle cell disease. Often referred to as "crises," these episodes are the principal cause of morbidity among these patients. Although Western observers named sickle cell anemia for its curious microscopical morphologic features, African cultures have named it for its painful episodes. In the Ga language of Ghana, for example, the disease is known as chwechweechwe —"relentless, repetitive chewing." 1 Despite the obvious importance of this clinical syndrome, we know little about its epidemiologic characteristics. Here we report the findings of the National Heart, Lung and Blood Institute's Cooperative . . .