Details

Autor(en) / Beteiligte

• Feeley, T.Martin
• Leen, Edward J.
• Colgan, Mary-Paula
• Moore, Dermot J.
• Hourihane, Dermot O'Brien
• Shanik, Gregor D.

Titel

Histologic characteristics of carotid artery plaque

Ist Teil von

• Journal of vascular surgery, 1991-05, Vol.13 (5), p.719-724

Ort / Verlag

New York, NY: Mosby, Inc

Erscheinungsjahr

1991

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Carotid plaque characteristics associated with the production of symptoms were identified with quantification of carotid plaque constituents in high-grade stenotic asymptomatic (n = 8) and symptomatic (n = 44) plaques. Asymptomatic plaques contained significantly more fibrous/collagen material (88%) than symptomatic plaques (66%) (p < 0.05). Hemorrhage constituted 2% and 1% of asymptomatic and symptomatic plaques, respectively. The predominant nonfibrous material was a pink amorphous material mixed with cholesterol, which composed 7% of asymptomatic and 27% of symptomatic plaques (p < 0.05). No relationship was found between plaque composition and the number of ipsilateral ischemic neurologic events, nor was there evidence of a healing process. B-mode ultrasound scanning had a sensitivity of 94% in identifying plaque with > 80% fibrous content. We believe that plaque composition may be a useful discriminating factor in selecting asymptomatic patients for carotid endarterectomy.