Details

Autor(en) / Beteiligte

• Romero, Roberto
• Hanaoka, Shuichi
• Mazor, Moshe
• Athanassiadis, Apostolos P.
• Callahan, Robert
• Hsu, Yu Chiung
• Avila, Cecilia
• Nores, Jose
• Jimenez, Carlos

Titel

Meconium-stained amniotic fluid: A risk factor for microbial invasion of the amniotic cavity

Ist Teil von

• American journal of obstetrics and gynecology, 1991-03, Vol.164 (3), p.859-862

Ort / Verlag

Philadelphia, PA: Mosby, Inc

Erscheinungsjahr

1991

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• The purpose of this study was to determine whether meconium-stained amniotic fluid is a marker for microbial invasion of the amniotic cavity. Amniocentesis was performed on 707 patients presenting with preterm labor and intact membranes. Meconium-stained amniotic fluid was present in 4.2% (30/707) of patients with preterm labor. The prevalence of positive amniotic fluid cultures was significantly higher in women with meconium-stained amniotic fluid than in women with clear fluid (33% [10/30] vs 11% [75/677]; p = 0.001; odds ratio = 4.01; 95% confidence interval = 1.6 to 9.4). Patients with meconium-stained amniotic fluid were also more likely to have failed tocolysis and delivered a preterm neonate more frequently than patients with clear fluid (83% [25/30] vs 38% (258/677); p = 0.0001; odds ratio = 8.1; 95% confidence interval = 2.9 to 24.4). We conclude that meconium-stained amniotic fluid is a risk factor for microbial invasion of the amniotic cavity and preterm delivery in women with preterm labor and intact membranes.