Details

Autor(en) / Beteiligte

• Murphy, Judith H
• Barlai-Kovach, Martha M
• Mathews, Robert A
• Beerman, Lee B
• Park, Sang C
• Neches, William H
• Zuberbuhler, James R

Titel

Rest and exercise right and left ventricular function late after the mustard operation: Assessment by radionuclide ventriculography

Ist Teil von

• The American journal of cardiology, 1983-01, Vol.51 (9), p.1520-1526

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

1983

Quelle

Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)

Beschreibungen/Notizen

• To evaluate ventricular function late after atrial repair of transposition of the great arteries (TGA), 26 asymptomatic patients had rest and exercise radionuclide ventriculography performed a mean of 9 years (range 5 to 15) after undergoing the Mustard operation. The mean resting right (systemic) ventricular (RV) ejection fraction (EF) was 0.50 ± 0.10 (±1 standard deviation); the RVEF was <0.45 in 8 patients. With exercise the RVEF increased in 9 patients and either failed to increase or decreased in 15 (including all 8 patients with resting values <0.45). The weight-adjusted work load performed was a first predictor of RV exercise response (sensitivity 87%, specificity 92%); patients whose RVEF increased did more work. The mean resting left (pulmonary) ventricular (LV) EF was 0.58 ± 0.09; the LVEF was <0.50 in 3 patients. With exercise the LVEF increased in 14 patients and did not increase in 10 (including all 3 with resting values <0.50). The presence of complex ventricular arrhythmia documented on Holter monitoring was a first predictor of failure of the LVEF to increase with exercise (sensitivity 84%, specificity 71%). The patient's age, operative age, postoperative interval, residual arterial desaturation, preoperative large ventricular septal defect or pulmonary stenosis, postoperative pulmonary stenosis or superior vena caval obstruction, or performance of a second open-heart procedure was predictive of the rest or exercise EF of either ventricle.