The American journal of clinical nutrition, 1991-01, Vol.53 (1), p.314S-321S
1991
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Details
- Autor(en) / Beteiligte
- Titel
- Role of vitamin E in preventing the oxidation of low-density lipoprotein
- Ist Teil von
- The American journal of clinical nutrition, 1991-01, Vol.53 (1), p.314S-321S
- Ort / Verlag
- Bethesda, MD: Elsevier Inc
- Erscheinungsjahr
- 1991
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- The fatty acid composition, antioxidants, and the oxidation resistance of the low-density lipoproteins (LDL) from a number of different donors were determined. The oxidation resistance of LDL, as determined in vitro by the duration of the lag-phase in copper ion-induced oxidation, did not correlate with the α-tocopherol content of the LDL. By supplementating plasma with vitamin E, the a-tocopherol content of LDL could be increased from ∼9 to 30 mol/mol LDL and also the oxidative resistance increased nearly linearly with increasing α-tocopherol content. The results indicate that α-tocopherol is an important, yet not the only parameter that determines the oxidation resistance of LDL.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0002-9165eISSN: 1938-3207DOI: 10.1093/ajcn/53.1.314STitel-ID: cdi_proquest_miscellaneous_80360150
- Format
- –
- Schlagworte
- Adult, Antioxidants - metabolism, atherosclerosis, Biological and medical sciences, Fatty Acids - analysis, Fatty Acids - metabolism, Fatty Acids, Unsaturated - analysis, Fatty Acids, Unsaturated - metabolism, Female, Fundamental and applied biological sciences. Psychology, Humans, Lipid Peroxidation, Lipoproteins, LDL - analysis, Lipoproteins, LDL - metabolism, low density lipoprotein, Male, Oxidation-Reduction, Vertebrates: anatomy and physiology, studies on body, several organs or systems, Vitamin E, Vitamin E - pharmacology