Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist gegebenenfalls nur via VPN oder Shibboleth (DFN-AAI) möglich. mehr Informationen...
Reliability of the porphobilinogen screening assay
Ist Teil von
Pathology, 1990, Vol.22 (4), p.197-198
Ort / Verlag
England: Elsevier B.V
Erscheinungsjahr
1990
Quelle
Taylor & Francis Journals Auto-Holdings Collection
Beschreibungen/Notizen
A survey conducted by the Australian Association of Clinical Biochemists Porphyrin Working Party on urinary porphobilinogen screening showed good sensitivity (75-97.5%). This is contrary to reports in the literature and to our own observations. We therefore assessed a widely used screening method (Watson-Schwartz) and found poor sensitivity (40-69%), and even less sensitivity (28-53%) when the urine samples were normally coloured or concentrated. Thus the results obtained by the Working Party might mislead one to infer that the Watson-Schwartz method is reliable.