Details

Autor(en) / Beteiligte

• Pupita, Giuseppe
• Maseri, Attilio
• Kaski, Juan Carlos
• Galassi, Alfredo R
• Gavrielides, Stavros
• Davies, Graham
• Crea, Filippo

Titel

Myocardial Ischemia Caused by Distal Coronary-Artery Constriction in Stable Angina Pectoris

Ist Teil von

• The New England journal of medicine, 1990-08, Vol.323 (8), p.514-520

Ort / Verlag

Boston, MA: Massachusetts Medical Society

Erscheinungsjahr

1990

Quelle

MEDLINE

Beschreibungen/Notizen

• IN patients with chronic stable angina, several studies 1 2 3 4 have shown that many episodes of ST-segment depression during daily life are not preceded by an increase in heart rate, or occur at a heart rate much lower than that required to trigger myocardial ischemia during exercise (or both). Because changes in caliber at the site of critical or subcritical coronary stenoses have been documented angiographically in response to exercise, 5 , 6 vasodilators, 7 , 8 and vasoconstrictors, 9 the variability of the ischemic threshold that is frequently observed in patients with stable angina is often attributed to such changes. However, a recent detailed postmortem study 10 suggested that . . .