Cancer, 1990-05, Vol.65 (10), p.2266-2269
1990
Details
- Autor(en) / Beteiligte
- Titel
- Intratumoral heterogeneity of DNA content in lung cancer
- Ist Teil von
- Cancer, 1990-05, Vol.65 (10), p.2266-2269
- Ort / Verlag
- New York: Wiley Subscription Services, Inc., A Wiley Company
- Erscheinungsjahr
- 1990
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Heterogeneity of DNA content was analyzed in 208 samples from 20 resected lung tumors. Only one carcinoma was homogeneously diploid, but the others had DNA aneuploidy in at least some tissue samples. Eighteen tumors (90%) had varying degrees of heterogeneity of DNA content. Over half of these could have been mislabeled as diploid if the tumors had not been widely sampled. The importance of adequate sampling in assessing ploidy status of lung tumors is emphasized.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0008-543XeISSN: 1097-0142DOI: 10.1002/1097-0142(19900515)65:10<2266::AID-CNCR2820651018>3.0.CO;2-RTitel-ID: cdi_proquest_miscellaneous_79798703
- Format
- –
- Schlagworte
- Adenocarcinoma - genetics, Aged, Biological and medical sciences, Carcinoid Tumor - genetics, Carcinoma - genetics, DNA, Neoplasm - analysis, Female, Flow Cytometry, Humans, Lung Neoplasms - genetics, Lung Neoplasms - pathology, Male, Medical sciences, Middle Aged, Ploidies, Pneumology, Tumors of the respiratory system and mediastinum