Bioorganic & medicinal chemistry, 1998, Vol.6 (1), p.31-41
1998
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Details
- Autor(en) / Beteiligte
- Titel
- Further antineoplastic terpenylquinones and terpenylhydroquinones
- Ist Teil von
- Bioorganic & medicinal chemistry, 1998, Vol.6 (1), p.31-41
- Ort / Verlag
- England: Elsevier Ltd
- Erscheinungsjahr
- 1998
- Quelle
- Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)
- Beschreibungen/Notizen
- Influences of the quinone/hydroquinone fragment and other structural features are considered in relation with the antineoplastic activity and selectivity of terpenylquinones/hydroquinones. Several compounds have shown IC 50 values under the μM level. Influences of the quinone/hydroquinone fragments and other structural aspects are considered in relation with the antineoplastic activity and selectivity of terpenylquinones. Several compounds have shown IC 50 values under μM levels.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0968-0896eISSN: 1464-3391DOI: 10.1016/S0968-0896(97)10007-4Titel-ID: cdi_proquest_miscellaneous_79722954
- Format
- –
- Schlagworte
- Animals, antineoplastic, Antineoplastic Agents - chemical synthesis, Antineoplastic Agents - pharmacology, Avarol, Cell Death - drug effects, cytotoxicity, Humans, Hydroquinones - chemical synthesis, Hydroquinones - pharmacology, Magnetic Resonance Spectroscopy, Mice, Quinones - chemical synthesis, Quinones - pharmacology, Structure-Activity Relationship, Terpenes - chemical synthesis, Terpenes - pharmacology, terpenyl-naphthoquinones/naphthohydroquinones, Tumor Cells, Cultured - drug effects