Details

Autor(en) / Beteiligte

• Acosta, Anibal A.
• Oehninger, Sergio
• Hammer, Jeffrey
• Muasher, Suheil J.
• Liang, Hong Mei
• Jones, Debra L.

Titel

Preclinical abortions: incidence and significance in the Norfolk in vitro fertilization program

Ist Teil von

• Fertility and sterility, 1990-04, Vol.53 (4), p.673-676

Ort / Verlag

New York, NY: Elsevier Inc

Erscheinungsjahr

1990

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Clinical and prognostic significance of preclinical abortions in assisted reproduction is ill defined. Strict diagnostic criteria include a transient and synchronous elevation of serum β-human chorionic gonadotropin (hCG), estradiol, and progesterone levels 13 days after hCG administration, ending in a bleeding episode no more than 14 days after the missed period. The preclinical abortion study group (54 patients, 178 cycles) was compared with matched control groups A (54 patients, 132 cycles) and B (54 patients, 155 cycles), representing normal term pregnancies and all outcomes, respectively. Control group C included the overall population during the study period. The abortion rate per transfer (preclinical abortion and total miscarriage rates) and total pregnancy wastage in the study group were significantly higher; the ongoing pregnancy rate was significantly lower. Preclinical abortion should be considered as a true reproductive failure with similar implications.