Details

Autor(en) / Beteiligte

• Tsutsu, Nobutaka
• Nunoi, Kiyohide
• Yokomizo, Yoshifumi
• Kikuchi, Masanori
• Fujishima, Masatoshi

Titel

Relationship between glycemic control and orthostatic hypotension in type 2 diabetes mellitus — a survey by the Fukuoka Diabetes Clinic Group

Ist Teil von

• Diabetes research and clinical practice, 1990, Vol.8 (2), p.115-123

Ort / Verlag

Ireland: Elsevier Ireland Ltd

Erscheinungsjahr

1990

Link zum Volltext

Quelle

Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)

Beschreibungen/Notizen

• We examined the prevalence of orthostatic hypotension and its association with glycemic control, as assessed by hemoglobin A 1 (HbA 1) concentration, in type 2 diabetic patients. The prevalence of orthostatic hypotension in 886 diabetics who were referred to our study and in 587 diabetics who were not given any antihypertensive drugs was 7% and 6%, respectively. The relationship between orthostatic hypotension and HbA 1 levels was evaluated only in subjects not receiving antihypertensive drugs, since antihypertensive agents might induce orthostatic hypotension. HbA 1 levels were 11.0 ± 2.1% in the diabetic patients with orthostatic hypotension, which was significantly higher than the HbA 1 levels of 9.9 ± 2.2% in the diabetic patients without orthostatic hypotension. Multivariate analysis also revealed that the association remained significant after adjustment for the treatment and duration of diabetes, age, sex and body mass index. These findings suggest that glycemic control contributes to the development of orthostatic hypotension in type 2 diabetic patients.