Details

Autor(en) / Beteiligte

• Rutkove, Seward B.
• Kothari, Milind J.
• Raynor, Elizabeth M.
• Levy, Michele L.
• Fadic, Ricardo
• Nardin, Rachel A.

Titel

Sural/radial amplitude ratio in the diagnosis of mild axonal polyneuropathy

Ist Teil von

• Muscle & nerve, 1997-10, Vol.20 (10), p.1236-1241

Ort / Verlag

New York: John Wiley & Sons, Inc

Erscheinungsjahr

1997

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• As proximal nerves are relatively spared in length‐dependent, axonal polyneuropathy, we theorized that a sural/radial amplitude ratio (SRAR) might be a sensitive indicator of mild polyneuropathy. In this study, sural amplitudes and SRARs in patients with signs of mild axonal polyneuropathy were compared to those of normal, age‐matched control subjects. Sural and radial sensory responses were measured in a standard fashion in all subjects. Thirty polyneuropathy patients had an average SRAR of 0.29 as compared to 0.71 for the 30 normal subjects. An SRAR of less than 0.40 was a strong predictor of axonal polyneuropathy, with 90% sensitivity and 90% specificity, as compared to an absolute sural amplitude of less than 6.0 μV, which had sensitivity of only 66%. Additionally, unlike the sural amplitude, the ratio did not vary significantly with age. We conclude that the SRAR is a sensitive, specific, age‐independent electrodiagnostic test for mild axonal polyneuropathy. © 1997 John Wiley & Sons, Inc. Muscle Nerve 20: 1236–1241, 1997