Details

Autor(en) / Beteiligte

• Marco, A. Dr
• Campostrini, F.
• Garusi, G. F.

Titel

Non-Hodgkin Lymphomas Presenting with Spinal Epidural Involvement

Ist Teil von

• Acta oncologica, 1989, Vol.28 (4), p.485-488

Ort / Verlag

Basingstoke: Informa UK Ltd

Erscheinungsjahr

1989

Quelle

MEDLINE

Beschreibungen/Notizen

• Spinal cord compression was the presenting symptom in 9 out of 299 previously undiagnosed non-Hodgkin lymphomas observed between 1972 and 1987. All patients had unfavourable histologic diagnosis and 4 had stage IE, 2 stage IIE and 2 were staged as IV; one patient did not undergo a staging procedure. All patients were treated with surgery and radiotherapy, whereas chemotherapy was employed in 3 cases only. Only 2 patients are still alive and disease-free after 3 and 8 years respectively; the remaining 7 died with progression of disease, even if in 2 cases a complete clinical remission was obtained. the recent literature has been reviewed. Non-Hodgkin lymphoma with spinal epidural presentation is usually an aggressive disease. An intensive treatment combining surgery, radiotherapy and chemotherapy is finally suggested to achieve better local and long-term results. Surgery can as a rule be limited to laminectomy plus biopsy.