Free radical biology & medicine, 1989, Vol.6 (3), p.285-288
1989
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Details
- Autor(en) / Beteiligte
- Titel
- Comparative free-radical chemistry in the radiolytic deamination and dephosphorylation of bio-organic molecules, I oxygen-free solutions
- Ist Teil von
- Free radical biology & medicine, 1989, Vol.6 (3), p.285-288
- Ort / Verlag
- New York, NY: Elsevier Inc
- Erscheinungsjahr
- 1989
- Quelle
- Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)
- Beschreibungen/Notizen
- A wide range of experimental data is evaluated in support of the hypothesis that the reductive deamination of amino acids and peptides by e aq − and the oxidation dephosphorylation of glycol phosphates by OH in oxygen free solution are related in terms of a common elimination reaction involving free-radical intermediates of the same genre, that is, XCH(R) C dot (OH)R → HX+ C dot H(R)COR where X = NH 2, RCONH, and H 2 PO 4 respectively. The proposed reaction model unifies for the first time the basic free-radical chemistry of NC and POC bond cleavage in the radiolysis of peptides and glycol phosphates including proteins and nucleic acids in oxygen-free solution.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0891-5849eISSN: 1873-4596DOI: 10.1016/0891-5849(89)90055-5Titel-ID: cdi_proquest_miscellaneous_79076911
- Format
- –
- Schlagworte
- Amino Acids - metabolism, Chemical Phenomena, Chemistry, DNA, Exact sciences and technology, Free radical, Free Radicals, Glycols - metabolism, Inorganic chemistry and origins of life, Kinetics and mechanism of reactions, Main-chain scission, Molecular Structure, Oxidation-Reduction, Peptides, Peptides - metabolism, Phosphate esters, Phosphates - metabolism, Phosphorylation, Proteins, Pulse Radiolysis, Radiolysis, Solutions