Details

Autor(en) / Beteiligte

• Grodstein, Francine
• Stampfer, Meir J
• Colditz, Graham A
• Willett, Walter C
• Manson, JoAnn E
• Joffe, Marshall
• Rosner, Bernard
• Fuchs, Charles
• Hankinson, Susan E
• Hunter, David J
• Hennekens, Charles H
• Speizer, Frank E

Titel

Postmenopausal Hormone Therapy and Mortality

Ist Teil von

• The New England journal of medicine, 1997-06, Vol.336 (25), p.1769-1776

Ort / Verlag

Boston, MA: Massachusetts Medical Society

Erscheinungsjahr

1997

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Whether to take postmenopausal hormones is a difficult decision. Hormone use carries many benefits, including decreased risks of osteoporosis 1 and cardiovascular disease, 2 as well as hazards, especially an increase in the risks of breast and endometrial cancers. 1 Observational studies have reported reduced mortality among women taking hormones, 3 – 9 but many of the studies have had methodologic flaws that limit firm conclusions. Specifically, women for whom estrogens are prescribed are often healthier initially, and those who continue to take hormones tend to be free of disease (for example, women in whom cancer is diagnosed often stop taking hormones). 8 , 10 , 11 Thus, . . .