Details

Autor(en) / Beteiligte

• WINK, T
• VAN ZUILEN, S. J
• BULT, A
• VAN BENNEKOM, W. P

Titel

Self-assembled monolayers for biosensors

Ist Teil von

• Analyst (London), 1997-04, Vol.122 (4), p.43R-50R

Ort / Verlag

Cambridge: Royal Society of Chemistry

Erscheinungsjahr

1997

Quelle

MEDLINE

Beschreibungen/Notizen

• The use of self-assembled monolayers (SAMs) in various fields of research is rapidly growing. In particular, many biomedical fields apply SAMs as an interface-layer between a metal surface and a solution or vapour. This review summarises methods for the formation of SAMs upon the most commonly used materials and techniques used for monolayer characterisation. Emphasis will lie on uniform, mixed and functionalised monolayers applied for immobilisation of biological components including (oligo-)nucleotides, proteins, antibodies and receptors as well as polymers. The application of SAMs in today's research, together with some applications will be discussed.